⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940070 | 0.90 | EPHX1 (0.38) | — | |
| SCHEMBL940071 | 0.90 | EPHX1 (0.38) | — | |
| SCHEMBL1051109 | 0.89 | — | — | |
| SCHEMBL7747239 | 0.89 | — | — | |
| SCHEMBL939875 | 0.87 | KDM4E (0.48) | — | |
| SCHEMBL7747093 | 0.87 | KDM4E (0.48) | — | |
| SCHEMBL7748472 | 0.87 | KDM4E (0.48) | — | |
| SCHEMBL8491948 | 0.85 | — | — | |
| SCHEMBL3638472 | 0.74 | — | — | |
| SCHEMBL20294037 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | claimed |
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-07-06 | — | — | US | claimed |
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | claimed |
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | claimed |
| CN-115697996-A | Alkenyl pyrimidine compound, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| WO-2021238827-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-02 | — | — | WO | claimed |
| CN-113717156-A | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2021-11-30 | — | — | CN | claimed |
| US-20040077549-A1 | Inhibitors of the E2F-1/cyclin interaction for cancer therapy | BAIR KENNETH WALTER (US) | 2004-04-22 | — | — | US | claimed |
| US-20040053849-A1 | Inhibitors of the E2F-1/cyclin interaction for cancer therapy | BAIR KENNETH WALTER (US) | 2004-03-18 | — | — | US | claimed |
| EP-1345957-A2 | INHIBITORS OF THE E2F-1/CYCLIN INTERACTION FOR CANCER THERAPY | Novartis AG (CH) | 2003-09-24 | — | — | EP | claimed |
| US-20020142966-A1 | Inhibitors of the E2F-1/cyclin interaction for cancer therapy | BAIR KENNETH WALTER (US) | 2002-10-03 | — | — | US | claimed |
| WO-2002050102-A2 | INHIBITORS OF THE E2F-1/CYCLIN INTERACTION FOR CANCER THERAPY | NOVARTIS AG (CH) | 2002-06-27 | — | — | WO | claimed |
| US-5834450-A | 9- (substituted amino) -alpha-6-deoxy-5-oxy tetracycline derivatives, their preparation and their use as antibiotics | PFIZER INC. (US) | 1998-11-10 | — | — | US | claimed |
| EP-0745065-A1 | 9-(SUBSTITUTED AMINO)-ALPHA-6-DEOXY-5-OXY TETRACYCLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS | PFIZER INC. (US) | 1996-12-04 | — | — | EP | claimed |
| WO-1995022529-A1 | 9-(SUBSTITUTED AMINO)-ALPHA-6-DEOXY-5-OXY TETRACYCLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS | PFIZER INC. (US) | 1995-08-24 | — | — | WO | claimed |
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | disclosed |
| EP-0622361-A1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |