Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819518 | 0.93 | POLB (0.47) | TP53CNR2POLBKDM4EMAPT | |
| SCHEMBL28819577 | 0.90 | CNR2 (0.43) | TP53CNR2POLBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4222818 | 0.89 | MCHR1 (0.43) | CNR2KDM4E | |
| SCHEMBL28819642 | 0.88 | MCHR1 (0.44) | CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL4222816 | 0.88 | MCHR1 (0.42) | KDM4E | |
| SCHEMBL28819631 | 0.86 | CNR2 (0.45) | TP53CNR2KDM4EMAPTALDH1A1 | |
| SCHEMBL28948675 | 0.86 | KDM4E (0.48) | TP53KDM4EHSD17B10USP2MAPT | |
| Hydrochloric Acid SCHEMBL4213341 | 0.85 | CNR2 (0.49) | TP53CNR2KDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL4216436 | 0.84 | MCHR1 (0.46) | TP53CNR2MAPTALDH1A1FPR2 | |
| SCHEMBL28819721 | 0.84 | KDM4E (0.42) | TP53CNR2KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |