Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.67 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.50 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896952 | 0.94 | ALK (0.68) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897383 | 0.91 | ALK (0.72) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897532 | 0.86 | ALK (0.74) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL10272635 | 0.85 | ALK (0.67) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL20366584 | 0.84 | ALK (0.61) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL28017466 | 0.83 | ALK (0.62) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL24676643 | 0.81 | ALK (0.59) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL21443164 | 0.81 | ALK (0.60) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL896697 | 0.81 | ALK (1.00) | ALK | |
| SCHEMBL898223 | 0.81 | ALK (0.77) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459172-B | Tetracyclic compound | CHUGAI PHARMACEUTICAL CO LTD | 2015-06-24 | — | — | CN | disclosed |