Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27964125 | 0.80 | HCAR2 (0.49) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL27983388 | 0.79 | HCAR2 (0.48) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL27977175 | 0.75 | MKNK1 (0.54) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL30558789 | 0.75 | MKNK1 (0.54) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL5287550 | 0.74 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL6916834 | 0.72 | NEK1 (0.47) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL31333678 | 0.70 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL4457723 | 0.70 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL27983075 | 0.70 | HCAR2 (0.50) | HCAR2HCAR3MKNK1MKNK2IGF1R | |
| SCHEMBL31334476 | 0.70 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672250-A | Substituted ceteroary compound as well as composition and purpose thereof | GUANGDONG HEC PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |