SCHEMBL28820544

SCHEMBL28820544

CCCCCn1nc(C(=O)NCC(C)CO)cc1-c1cccs1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 6/20 0.48
CNR1 P21554 13/20 0.43
CNR2 P34972 11/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28820643 0.99 SMPD1 (0.49) SMPD1CNR1CNR2
SCHEMBL28820551 0.97 SMPD1 (0.44) SMPD1CNR1CNR2
SCHEMBL28820569 0.83 SMPD1 (0.50) SMPD1CNR1CNR2
SCHEMBL28820557 0.81 SMPD1 (0.48) SMPD1CNR1CNR2
SCHEMBL28820635 0.79 CNR1 (0.65) SMPD1CNR1CNR2
SCHEMBL28820549 0.77 CNR1 (0.66) CNR1CNR2
SCHEMBL28820525 0.76 CNR1 (0.66) CNR1CNR2
SCHEMBL28820553 0.75 CNR1 (0.64) SMPD1CNR1CNR2
SCHEMBL28820728 0.75 CNR1 (0.67) SMPD1CNR1CNR2
SCHEMBL28948773 0.73 CNR1 (0.65) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109516955-B Nitrogen-containing five-membered aromatic heterocyclic compound and preparation method and application thereof 华东师范大学 2022-07-26 CN claimed
CN-109516955-B Nitrogen-containing five-membered aromatic heterocyclic compound and preparation method and application thereof 华东师范大学 2022-07-26 CN disclosed