Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872197 | 0.90 | GRN (0.59) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL28820734 | 0.82 | CNR1 (0.53) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL28820595 | 0.82 | CNR1 (0.65) | GRNSORT1CNR1CNR2MAPK14 | |
| SCHEMBL11900405 | 0.80 | GRN (0.56) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL28820600 | 0.79 | CNR1 (0.52) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL25346695 | 0.78 | GRN (0.72) | GRNSORT1TDP1SMN1; SMN2POLB | |
| SCHEMBL3995561 | 0.75 | GRN (0.46) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL573823 | 0.75 | CNR1 (0.46) | GRNSORT1CNR1CNR2TDP1 | |
| SCHEMBL574357 | 0.75 | GRN (0.46) | GRNSORT1CNR1CNR2TDP1 | |
| Benzoic Acid Hexyl Ester SCHEMBL27461048 | 0.73 | TDP1 (0.71) | CNR2TDP1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516955-B | Nitrogen-containing five-membered aromatic heterocyclic compound and preparation method and application thereof | 华东师范大学 | 2022-07-26 | — | — | CN | disclosed |