Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.44 |
| ▸ | CNR2 | P34972 | 16/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820601 | 0.95 | CNR1 (0.46) | CNR1CNR2PSMB8PSMB9PSMB5 | |
| SCHEMBL28820553 | 0.81 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL28820582 | 0.81 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL28820568 | 0.80 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL28820576 | 0.80 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL28820567 | 0.80 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL28820596 | 0.80 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL28820548 | 0.78 | NTRK1 (0.41) | CNR1CNR2PDE10A | |
| SCHEMBL28820585 | 0.77 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL28820635 | 0.74 | CNR1 (0.65) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516955-B | Nitrogen-containing five-membered aromatic heterocyclic compound and preparation method and application thereof | 华东师范大学 | 2022-07-26 | — | — | CN | disclosed |