Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21842845 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL28571943 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL28573898 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL28573267 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL7681688 | 0.97 | TSHR (0.55) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL14395271 | 0.95 | TSHR (0.55) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL28337020 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL1885691 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1DNM1THRB | |
| SCHEMBL1883604 | 0.95 | TSHR (0.68) | TSHRALDH1A1TDP1DNM1THRB | |
| Butyl Chloride SCHEMBL875688 | 0.95 | TSHR (0.60) | TSHRALDH1A1TDP1DNM1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907261-B | 2-phenylaminoquinoline derivative, preparation method and application thereof | 湖南中医药大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113845485-B | Amino acid derivative and preparation method and application thereof | 湖南中医药大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-114907261-A | 2-phenylamino quinoline derivative and preparation method and application thereof | 湖南中医药大学 | 2022-08-16 | — | — | CN | disclosed |