Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 7/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588325 | 0.89 | FLT4 (0.56) | FLT4KDRCDK1CDK2PTK2 | |
| SCHEMBL15524161 | 0.89 | FLT4 (0.56) | FLT4KDRCDK1CDK2PTK2 | |
| SCHEMBL28024447 | 0.86 | FLT4 (0.73) | FLT4PTK2 | |
| SCHEMBL15506743 | 0.81 | FLT4 (0.71) | FLT4KDR | |
| SCHEMBL15588326 | 0.79 | FLT4 (0.73) | FLT4PTK2 | |
| SCHEMBL15524187 | 0.79 | FLT4 (0.73) | FLT4PTK2 | |
| SCHEMBL15588323 | 0.76 | FLT4 (0.76) | FLT4PTK2 | |
| SCHEMBL15588327 | 0.76 | FLT4 (0.72) | FLT4PTK2 | |
| SCHEMBL15524361 | 0.76 | FLT4 (0.72) | FLT4PTK2 | |
| SCHEMBL1627765 | 0.76 | FLT4 (0.58) | FLT4KDRCDK1CDK2PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837835-A | VEGFR3 inhibitors | CANCER THERAPEUTICS CRC PTY LTD | 2015-08-12 | — | — | CN | disclosed |