Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29880702 | 1.00 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL12081341 | 0.83 | POLB (0.65) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL27376419 | 0.83 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL17067758 | 0.83 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL30806307 | 0.83 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL15712170 | 0.83 | HDAC1 (0.69) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL11062154 | 0.83 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL15718654 | 0.83 | POLB (0.68) | POLBHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL29880432 | 0.82 | POLB (1.00) | POLBMEN1KMT2ACYP1A2GAA | |
| SCHEMBL10688767 | 0.82 | POLB (1.00) | POLBMEN1KMT2ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015952-B | Diaryl methane compound and preparation method and application thereof | 北京大学深圳研究生院 | 2022-08-19 | — | — | CN | disclosed |