SCHEMBL28823315

SCHEMBL28823315

Cc1cn(Cn2ccc(N)nc2=O)c(=O)nc1N

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.40
EP300 Q09472 15/20 0.37
SLC22A6 Q4U2R8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16446911 0.83 FGFR1 (0.47) FGFR1EP300SLC22A6
SCHEMBL27707200 0.77 EP300 (0.42) EP300
SCHEMBL11718699 0.75 EP300 (0.43) EP300
SCHEMBL24709494 0.73 FGFR1 (0.44) FGFR1EP300SLC22A6
SCHEMBL236000 0.73 FGFR1 (0.51) FGFR1EP300SLC22A6
SCHEMBL1892698 0.73 FGFR1 (0.44) FGFR1EP300SLC22A6
SCHEMBL21546149 0.72 EP300 (0.44) EP300
SCHEMBL22039144 0.72 SOS1 (0.47) EP300
SCHEMBL19711602 0.71 EP300 (0.40) EP300
SCHEMBL20919715 0.71 FGFR1 (0.46) FGFR1EP300SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114651070-A Structure and temperature dependent flap endonuclease substrates 精密科学公司 2022-06-21 CN disclosed