Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108089 | 1.00 | DHODH (0.44) | DHODH | |
| SCHEMBL28823358 | 0.89 | DHODH (0.57) | DHODH | |
| SCHEMBL20108173 | 0.89 | DHODH (0.57) | DHODH | |
| SCHEMBL21918032 | 0.89 | DHODH (0.57) | DHODH | |
| SCHEMBL24390268 | 0.88 | DHODH (0.47) | DHODH | |
| SCHEMBL28953471 | 0.87 | DHODH (0.46) | DHODH | |
| SCHEMBL21853384 | 0.85 | DHODH (0.52) | DHODH | |
| SCHEMBL21853382 | 0.85 | DHODH (0.52) | DHODH | |
| SCHEMBL20107654 | 0.83 | DHODH (0.52) | DHODH | |
| SCHEMBL29816498 | 0.83 | DHODH (0.45) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |