Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.71 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.71 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.65 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823688 | 1.00 | PRMT5 (0.71) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL30018221 | 0.95 | CARM1 (0.70) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL28823752 | 0.88 | CARM1 (0.72) | PRMT5WDR77CARM1 | |
| SCHEMBL30124289 | 0.88 | CARM1 (0.72) | PRMT5WDR77CARM1 | |
| SCHEMBL28823758 | 0.86 | PRMT5 (0.71) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL28823826 | 0.85 | PRMT5 (0.71) | PRMT5WDR77CARM1 | |
| SCHEMBL28823825 | 0.85 | PRMT5 (0.71) | PRMT5WDR77CARM1 | |
| SCHEMBL23160171 | 0.84 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL23160168 | 0.84 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL29731442 | 0.84 | PRMT5 (1.00) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |