Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420871 | 1.00 | KAT8 (0.62) | KAT8PPARAPPARGTSHRALDH1A1 | |
| Pentane SCHEMBL27636475 | 0.99 | KAT8 (0.60) | KAT8PPARAPPARGTSHRALDH1A1 | |
| Hexane SCHEMBL28050986 | 0.95 | KAT8 (0.62) | KAT8PPARAPPARGTSHRALDH1A1 | |
| Octane SCHEMBL28857502 | 0.95 | KAT8 (0.62) | KAT8PPARAPPARGTSHRALDH1A1 | |
| SCHEMBL182437 | 0.95 | KAT8 (0.62) | KAT8PPARAPPARGTSHRALDH1A1 | |
| SCHEMBL27857274 | 0.94 | TSHR (0.57) | KAT8PPARAPPARGTSHRALDH1A1 | |
| Naphthalene SCHEMBL27271514 | 0.94 | TSHR (0.57) | KAT8PPARAPPARGTSHRALDH1A1 | |
| SCHEMBL27857277 | 0.94 | TSHR (0.57) | KAT8PPARAPPARGTSHRALDH1A1 | |
| SCHEMBL27807681 | 0.94 | KAT8 (0.55) | KAT8PPARAPPARGTSHRALDH1A1 | |
| Cyclohexane SCHEMBL27580700 | 0.94 | KAT8 (0.58) | KAT8PPARAPPARGTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348185-B | Bicyclic [3.2.1] octyl group amide derivatives and application thereof | H.隆德贝克有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105348185-A | Bicyclo[3.2.1]octyl amide derivatives and uses of same | LUNDBECK & CO AS H | 2016-02-24 | — | — | CN | disclosed |
| CN-103369961-B | Bicyclo [3.2.1] octylamide derivatives and uses thereof | H. LUNDBECK A/S (DK) | 2015-11-25 | — | — | CN | disclosed |