Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK1 | Q96PY6 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552445 | 0.85 | NEK1 (0.65) | NEK1 | |
| SCHEMBL2551348 | 0.84 | NEK1 (0.67) | NEK1 | |
| SCHEMBL15092548 | 0.83 | NEK1 (0.65) | NEK1 | |
| SCHEMBL2547066 | 0.81 | NEK1 (0.80) | NEK1 | |
| SCHEMBL2547607 | 0.79 | NEK1 (0.81) | NEK1 | |
| SCHEMBL2552444 | 0.76 | NEK1 (0.76) | NEK1 | |
| SCHEMBL2550248 | 0.74 | NEK1 (0.77) | NEK1 | |
| SCHEMBL2551345 | 0.74 | NEK1 (1.00) | NEK1 | |
| SCHEMBL2551413 | 0.73 | NEK1 (0.78) | NEK1 | |
| SCHEMBL2551470 | 0.72 | NEK1 (1.00) | NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102917590-B | Tricyclic compound and the PBK inhibitor containing described compound | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |