SCHEMBL28825980

SCHEMBL28825980

NC(Cc1ccccc1)(c1ccccc1)S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
HIF1A Q16665 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
SLC6A2 P23975 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
BLM P54132 1/20 0.41
GFER P55789 1/20 0.41
PMP22 Q01453 1/20 0.41
RECQL P46063 1/20 0.41
KIF11 P52732 2/20 0.40
MAPK1 P28482 1/20 0.40
CA1 P00915 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27560472 0.79 CYP2D6 (0.39) HIF1ACYP1A2CYP2C19TAAR1MAPT
SCHEMBL4958575 0.79 CYP2D6 (0.39) SMN1; SMN2HIF1ACYP1A2CYP3A4KDM4E
SCHEMBL2120252 0.79 CYP2D6 (0.39) SMN1; SMN2HIF1ACYP1A2CYP3A4KDM4E
SCHEMBL4958571 0.79 SMN1; SMN2 (0.53) SMN1; SMN2HIF1ACYP1A2CYP2C9CYP2C19
SCHEMBL27599832 0.78 CYP2C19 (0.48) SMN1; SMN2HIF1ACYP1A2CYP2C19ALDH1A1
SCHEMBL28031020 0.77 CYP1A2 (0.50) SMN1; SMN2HIF1ACYP1A2CYP2C9CYP2C19
SCHEMBL8934013 0.74 CYP1A2 (0.47) SMN1; SMN2HIF1ACYP1A2CYP2C9CYP2C19
Phentermine SCHEMBL28338903 0.73 SLC6A2 (0.76) SMN1; SMN2HIF1ACYP1A2SLC6A2TAAR1
SCHEMBL2120248 0.72 CYP1A2 (0.39) SMN1; SMN2HIF1ACYP1A2CYP3A4KDM4E
Phentermine SCHEMBL28815884 0.72 SLC6A2 (0.73) SMN1; SMN2HIF1ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114931141-A Synergistic fungicidal mixtures for controlling fungi in cereals 阿达玛马克西姆股份有限公司 2022-08-23 CN disclosed