SCHEMBL2882744

SCHEMBL2882744

CCC(=O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28229082 0.97
Bromide SCHEMBL23306700 0.97
Hydrochloric Acid SCHEMBL2824186 0.97
Hydrochloric Acid SCHEMBL23354040 0.97
SCHEMBL5860130 0.82 GABRR1 (0.55)
Hydrochloric Acid SCHEMBL11466725 0.77 TDP1 (0.83)
SCHEMBL2357325 0.76 TDP1 (1.00)
SCHEMBL1887087 0.76
SCHEMBL42679 0.76
SCHEMBL1226620 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108928831-A Molecular sieve SCM-16, its preparation method and use 中国石油化工股份有限公司 2018-12-04 CN claimed
CN-108928835-A The synthetic method of IWR structure molecular screen and its molecular sieve of synthesis 中国石油化工股份有限公司 2018-12-04 CN claimed
CN-108441162-A A kind of preparation method with colour change function polyurethane film 上海伟星光学有限公司 2018-08-24 CN claimed
US-9199944-B2 N2,N4-bis(4-(piperazine-1-yl)phenyl)pirimidine-2,4-diamine derivative or pharmaceutically acceptable salt thereof, and composition containing same as active ingredient for preventing or treating cancer KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-12-01 US claimed
EP-2883875-A1 N2,N4-BIS(4-(PIPERAZINE-1-YL)PHENYL)PIRIMIDINE-2,4-DIAMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER Korea Reserach Institute Of Chemical Technology (KR) 2015-06-17 EP claimed
US-20150152069-A1 N2,N4-BIS(4-(PIPERAZINE-1-YL)PHENYL)PIRIMIDINE-2,4-DIAMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER PINOTBIO, INC. (KR) 2015-06-04 US claimed
CN-101472917-A Benzimidazole 5-sulfonamide derivatives as cannabinoid 1 (CB1) receptor ligands ASTRAZENECA AB (SE) 2009-07-01 CN claimed
CN-1238344-C Method for preparing tetramethyl pyrazine LIVZON GROUP LIMIN PHARMACEUTI (CN) 2006-01-25 CN claimed
CN-1546474-A Method for preparing tetramethyl pyrazine 丽珠集团利民制药厂 2004-11-17 CN claimed
EP-1067894-A4 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2004-09-08 EP claimed
EP-1067894-A2 PROTEASE INHIBITORS SmithKline Beecham Corporation (US) 2001-01-17 EP claimed
WO-1999059526-A2 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-11-25 WO claimed
CN-1055925-A Pyridine derivate and preparation method thereof ICI PLC (GB) 1991-11-06 CN claimed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 US disclosed
CN-120114655-A Delivery of hydrophobic active agent particles 苏尔莫迪克斯公司 2025-06-10 CN disclosed
CN-119857095-A Choroidal neovascularization inhibitor or drusen inhibitor and its evaluation or screening method 林科杰诺米克斯股份有限公司 2025-04-22 CN disclosed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
US-5311426-A Apparatus and method for providing assay calibration data ABBOTT LABORATORIES (US) 1994-05-10 US disclosed
US-4326054-A ANTIBIOTIC AND ANTITUMOR AGENT ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-04-20 US disclosed
US-3956316-A PROGESTATIONAL AND SALT-RETAINING AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-05-11 US disclosed