SCHEMBL28828449

SCHEMBL28828449

CCCCc1ccc(-c2cc3c(cc2F)C(OC(N)=O)C(C)(C)C3)cc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.41
MPL P40238 7/20 0.38
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
FFAR4 Q5NUL3 3/20 0.35
S1PR1 P21453 2/20 0.35
POLB P06746 1/20 0.34
S1PR3 Q99500 1/20 0.33
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29121360 1.00 RARB (0.41) RARBMPLRARARARGFFAR4
SCHEMBL29121155 0.94 FFAR4 (0.36) RARBMPLRARARARGFFAR4
SCHEMBL28828611 0.94 FFAR4 (0.36) RARBMPLRARARARGFFAR4
SCHEMBL29121166 0.90 RARB (0.40) RARBMPLRARARARGFFAR4
SCHEMBL28828633 0.90 SLC6A2 (0.34) RARBFFAR4S1PR1
SCHEMBL29121290 0.90 SLC6A2 (0.34) RARBFFAR4S1PR1
SCHEMBL29121333 0.88 FFAR4 (0.41) RARBRARAFFAR4S1PR1S1PR3
SCHEMBL28828514 0.88 FFAR4 (0.41) RARBRARAFFAR4S1PR1S1PR3
SCHEMBL28828717 0.87 PPARG (0.36) RARBMPLFFAR4POLB
SCHEMBL29121253 0.87 FFAR4 (0.37) RARBMPLFFAR4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829361-B Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-07-16 CN claimed
CN-114829361-A Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same 柳韩洋行 2022-07-29 CN claimed
CN-114829361-B Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-07-16 CN disclosed
CN-114829361-A Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same 柳韩洋行 2022-07-29 CN disclosed