SCHEMBL2882906

SCHEMBL2882906

COC1CCN(CCc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc2)C1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.59
KCNH2 Q12809 5/20 0.59
HRH3 Q9Y5N1 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003118 1.00 MCHR1 (0.59) MCHR1KCNH2HRH3
SCHEMBL1003063 1.00 MCHR1 (0.59) MCHR1KCNH2HRH3
SCHEMBL2892791 0.92 MCHR1 (0.71) MCHR1KCNH2HRH3
SCHEMBL1004737 0.89 MCHR1 (0.63) MCHR1KCNH2HRH3
SCHEMBL1000730 0.89 MCHR1 (0.63) MCHR1KCNH2HRH3
SCHEMBL1000731 0.83 MCHR1 (0.82) MCHR1KCNH2HRH3
SCHEMBL1001938 0.83 MCHR1 (0.55) MCHR1KCNH2
SCHEMBL1001909 0.83 MCHR1 (0.55) MCHR1KCNH2
SCHEMBL2894221 0.80 MCHR1 (0.76) MCHR1KCNH2HRH3
SCHEMBL1002095 0.80 MCHR1 (0.59) MCHR1KCNH2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1921065-B1 PHENYLPYRIDONE DERIVATIVE BANYU PHARMA CO LTD (JP) 2010-10-20 EP disclosed