SCHEMBL28829161

SCHEMBL28829161

C#Cc1ccc(C(=O)O)c(-c2ccc(C3CCC(CCC)CC3)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
S1PR1 P21453 4/20 0.37
DGAT1 O75907 3/20 0.36
SOAT1 P35610 1/20 0.36
FFAR1 O14842 1/20 0.36
ESR2 Q92731 1/20 0.36
S1PR5 Q9H228 3/20 0.35
P2RY14 Q15391 3/20 0.35
ADRB3 P13945 2/20 0.35
ADRA2B P18089 2/20 0.35
DRD1 P21728 2/20 0.35
DRD5 P21918 2/20 0.35
ADRA1B P35368 2/20 0.35
TMEM97 Q5BJF2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7238872 0.85 CYP2C9 (0.43) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL2436428 0.84 CYP2C9 (0.51) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL2436430 0.84 CYP2C9 (0.51) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8676752 0.84 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8527592 0.84 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7510571 0.81 CYP2C9 (0.47) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8045331 0.81 CYP2C9 (0.47) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL11046109 0.80 CYP2C9 (0.46) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7239625 0.80 CYP2C9 (0.46) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7239619 0.80 CYP2C9 (0.46) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041275-B 4-propylcyclohexylbenzene derivative containing 1,2, 3-triazole five-membered ring and preparation method thereof 四川师范大学 2022-07-01 CN disclosed