Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863367 | 1.00 | MAPT (0.43) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL12484190 | 0.83 | MAPT (0.41) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL3661471 | 0.80 | CMA1 (0.38) | MAPTCYP3A4LMNARELACYP1B1 | |
| SCHEMBL27846245 | 0.78 | MAPT (0.43) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL27762380 | 0.77 | MAPT (0.42) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL27668573 | 0.76 | MAPT (0.41) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL27390431 | 0.75 | MAPT (0.46) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL28721825 | 0.73 | MAPT (0.44) | MAPTBCHECYP3A4RAB9ANPC1 | |
| SCHEMBL5323475 | 0.73 | CYP1B1 (0.47) | MAPTBCHECYP3A4RAB9ALMNA | |
| SCHEMBL28068325 | 0.73 | MAPT (0.44) | MAPTBCHECYP3A4RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693523-A | Chalcone derivate with 1,1-dichloropropene and preparation method and application thereof | 贵州大学 | 2016-06-22 | — | — | CN | disclosed |