Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | FDPS | P14324 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068287 | 1.00 | CA1 (0.53) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL21581984 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL27321446 | 0.92 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL8052116 | 0.92 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL15754145 | 0.92 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL8994069 | 0.92 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL1740005 | 0.90 | CA1 (0.59) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL7751076 | 0.86 | CA1 (0.52) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL27496364 | 0.86 | CA1 (0.52) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL27971921 | 0.86 | CA1 (0.52) | CA1ACE2ZDHHC7FAAHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928971-B | Aryl substituted aminotetrahydropyrans and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-105732636-A | Hetero-aromatic compounds and applications thereof in pharmacy | 广东东阳光药业有限公司 | 2016-07-06 | — | — | CN | disclosed |