Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 8/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829770 | 0.99 | EGFR (0.47) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829777 | 0.99 | HDAC3 (0.46) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829760 | 0.96 | EPHA2 (0.44) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829750 | 0.94 | EGFR (0.46) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829745 | 0.89 | HDAC3 (0.44) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829727 | 0.88 | HDAC3 (0.47) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829827 | 0.88 | HDAC3 (0.53) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829728 | 0.87 | HDAC3 (0.48) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829738 | 0.86 | HDAC3 (0.49) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28829722 | 0.86 | HDAC3 (0.49) | EGFRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835684-A | 4-aminoquinazoline compound containing morpholinyl aromatic heterocycle and hydroximic acid structure and preparation method thereof | 江苏食品药品职业技术学院 | 2022-08-02 | — | — | CN | disclosed |