SCHEMBL28829902

SCHEMBL28829902

COc1ccc(C2CC2CCCBr)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.59
KDM1A O60341 6/20 0.50
MAOA P21397 3/20 0.50
MAOB P27338 3/20 0.50
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43
TUBB8 Q3ZCM7 1/20 0.43
TUBA3E Q6PEY2 1/20 0.43
TUBA1A Q71U36 1/20 0.43
TUBA1C Q9BQE3 1/20 0.43
TUBB6 Q9BUF5 1/20 0.43
TUBB2B Q9BVA1 1/20 0.43
TUBB1 Q9H4B7 1/20 0.43
DRD2 P14416 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6056591 0.85 HTR2C (0.61) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL6056599 0.84 HTR2C (0.59) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL24529204 0.83 HTR2C (0.67) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL6250305 0.80 HTR2C (0.63) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL17346802 0.79 HTR2C (0.61) HTR2CKDM1AMAOAMAOBDRD2
SCHEMBL16591278 0.78 HTR2C (0.69) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL23995535 0.78 HTR2C (0.69) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL17985307 0.76 HTR2C (0.67) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL16585494 0.76 HTR2C (0.67) HTR2CKDM1AMAOAMAOBTUBB4A
SCHEMBL16585495 0.76 HTR2C (0.67) HTR2CKDM1AMAOAMAOBTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003110-B Aryl beta-aminoketone compound and preparation method thereof 南京工业大学 2022-09-06 CN claimed
CN-110003110-B Aryl beta-aminoketone compound and preparation method thereof 南京工业大学 2022-09-06 CN disclosed