SCHEMBL28829959

SCHEMBL28829959

CC1(C)CC1c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 17/20 0.52
MAOB P27338 15/20 0.52
MAOA P21397 14/20 0.52
BRD4 O60885 1/20 0.40
ALDH1A1 P00352 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4331068 0.86 KDM1A (0.67) KDM1AMAOBMAOA
Ammonia Solution, Strong SCHEMBL11017865 0.84 KDM1A (0.64) KDM1AMAOBMAOA
Cyanide SCHEMBL27790784 0.80 KDM1A (0.59) KDM1AMAOBMAOA
SCHEMBL31083620 0.78 KDM1A (0.45) KDM1AMAOBMAOAALDH1A1NPC1
Bicarbonate SCHEMBL10984022 0.78 KDM1A (0.57) KDM1AMAOBMAOA
SCHEMBL10981382 0.75 KDM1A (0.53) KDM1AMAOBMAOA
SCHEMBL20707753 0.75 MAOB (0.45) KDM1AMAOBMAOAALDH1A1
SCHEMBL15604958 0.74 KDM1A (0.47) KDM1AMAOBMAOA
SCHEMBL25212520 0.73 KDM1A (0.45) KDM1AMAOBMAOA
SCHEMBL20707745 0.73 KDM1A (0.45) KDM1AMAOBMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003110-B Aryl beta-aminoketone compound and preparation method thereof 南京工业大学 2022-09-06 CN claimed
CN-116905005-A Method for synthesizing 1, 3-oxyfluoride product by electrochemical mode 南京工业大学 2023-10-20 CN disclosed
CN-110003110-B Aryl beta-aminoketone compound and preparation method thereof 南京工业大学 2022-09-06 CN disclosed