SCHEMBL28830541

SCHEMBL28830541

Cc1ccccc1-c1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
MCL1 Q07820 1/20 0.43
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
AR P10275 1/20 0.40
TRPA1 O75762 1/20 0.39
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
TSHR P16473 4/20 0.38
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
ACHE P22303 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686606 1.00 CA12 (0.48) CA12CA1CA2CA9MCL1
SCHEMBL534043 0.96 CA12 (0.47) CA12CA1CA2CA9MCL1
SCHEMBL27571439 0.89 CA12 (0.43) CA12CA1CA2CA9MCL1
SCHEMBL27902263 0.88 CA12 (0.42) CA12CA1CA2CA9MCL1
SCHEMBL29212556 0.88 CA12 (0.42) CA12CA1CA2CA9MCL1
SCHEMBL29551646 0.86 CA12 (0.59) CA12CA1CA2CA9MCL1
SCHEMBL4541662 0.86 CA12 (0.59) CA12CA1CA2CA9MCL1
SCHEMBL29551674 0.83 CA12 (0.61) CA12CA1CA2CA9MCL1
SCHEMBL3633054 0.83 CA12 (0.61) CA12CA1CA2CA9MCL1
SCHEMBL3294993 0.81 CA12 (0.55) CA12CA1CA2CA9MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957304-A Chiral 1, 5-diborane compound and synthesis method and application thereof 浙江大学 2022-08-30 CN disclosed