SCHEMBL28831715

SCHEMBL28831715

CCOP(=O)(O)OC(=O)c1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.54
MAPT P10636 4/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
THRB P10828 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 1/20 0.47
ALDH1A1 P00352 5/20 0.46
MEN1 O00255 4/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
HSD17B10 Q99714 1/20 0.41
HPGD P15428 3/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6006322 0.87 NPC1 (0.46) KMT2AMAPTLMNAHTTTSHR
SCHEMBL17978252 0.86 KMT2A (0.56) KMT2AMAPTLMNAHTTTHRB
SCHEMBL570344 0.80 NPC1 (0.46) KMT2AMAPTLMNAHTTTSHR
SCHEMBL1569293 0.76 TSHR (0.80) KMT2AMAPTLMNAL3MBTL1TSHR
SCHEMBL29535471 0.76 TSHR (0.80) KMT2AMAPTLMNAL3MBTL1TSHR
SCHEMBL778657 0.76 KMT2A (0.51) KMT2AMAPTLMNAHTTTHRB
SCHEMBL779439 0.76 KMT2A (0.58) KMT2AMAPTLMNAHTTTHRB
SCHEMBL1549244 0.75 KMT2A (0.48) KMT2AMAPTLMNAHTTTHRB
SCHEMBL27501881 0.74 TSHR (0.77) KMT2AMAPTLMNAL3MBTL1TSHR
Methane SCHEMBL9674031 0.74 TSHR (0.65) KMT2AMAPTLMNAHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115029050-A UV (ultraviolet) curing coating and preparation method thereof 江苏恒隆通新材料科技有限公司 2022-09-09 CN claimed