Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.76 |
| ▸ | JAK1 | P23458 | 17/20 | 0.76 |
| ▸ | JAK3 | P52333 | 17/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445831 | 0.86 | JAK2 (1.00) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL30051820 | 0.82 | JAK2 (0.71) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL2866288 | 0.82 | JAK2 (0.71) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL16446258 | 0.82 | JAK2 (1.00) | JAK2JAK1JAK3 | |
| SCHEMBL16446232 | 0.81 | JAK2 (0.85) | JAK2JAK1JAK3 | |
| SCHEMBL16446317 | 0.81 | JAK2 (0.85) | JAK2JAK1JAK3 | |
| SCHEMBL16446248 | 0.76 | JAK2 (0.82) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL16446822 | 0.74 | JAK2 (1.00) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL16446777 | 0.73 | JAK2 (1.00) | JAK2JAK1JAK3HDAC1 | |
| SCHEMBL16446784 | 0.72 | JAK2 (0.81) | JAK2JAK1JAK3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837927-A | Preparation method of halogen-free flame-retardant polyolefin power cable | 扬州兰都塑料科技有限公司 | 2016-08-10 | — | — | CN | disclosed |