Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833248 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R2GAAALOX15 | |
| SCHEMBL26705625 | 0.90 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3R2ELANEHRH3 | |
| SCHEMBL16583313 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3R2ELANE | |
| SCHEMBL16583314 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3R2ELANE | |
| SCHEMBL28093334 | 0.86 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL16583238 | 0.86 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL28093332 | 0.86 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL16583237 | 0.86 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3R2 | |
| Hydrochloric Acid SCHEMBL22529309 | 0.85 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R2 | |
| Hydrochloric Acid SCHEMBL22529307 | 0.85 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924434-A | Substituted aminopyrimidine compound and usage method and application thereof | 广东东阳光药业有限公司 | 2016-09-07 | — | — | CN | disclosed |