⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164757 | 0.84 | — | — | |
| SCHEMBL28861502 | 0.83 | KDM4E (0.57) | — | |
| SCHEMBL9578184 | 0.83 | KDM4E (0.57) | — | |
| SCHEMBL28384258 | 0.75 | — | — | |
| SCHEMBL6567934 | 0.75 | — | — | |
| SCHEMBL28819734 | 0.74 | — | — | |
| SCHEMBL25360743 | 0.73 | — | — | |
| SCHEMBL3267815 | 0.73 | — | — | |
| SCHEMBL28250679 | 0.73 | — | — | |
| SCHEMBL28325031 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105916-B | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117105916-A | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-105916499-A | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2016-08-31 | — | — | CN | disclosed |