Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 3/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933502 | 1.00 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28834247 | 1.00 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL25130494 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28834207 | 0.88 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29933652 | 0.88 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28834206 | 0.88 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL23360649 | 0.86 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGKRAS | |
| SCHEMBL23360651 | 0.86 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGKRAS | |
| SCHEMBL25130570 | 0.84 | PDE4B (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL18497822 | 0.84 | IRAK4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |