Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834823 | 1.00 | MAOB (0.44) | MAOBMAOASOS1PDE2APDE10A | |
| SCHEMBL29901763 | 1.00 | MAOB (0.44) | MAOBMAOASOS1PDE2APDE10A | |
| SCHEMBL30230082 | 0.77 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL18551173 | 0.77 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL18551437 | 0.77 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL18551172 | 0.75 | MAOB (0.41) | MAOBMAOA | |
| SCHEMBL14311598 | 0.75 | SLC6A2 (0.55) | SOS1PDE2APDE10AGRM5LRRK2 | |
| SCHEMBL21443397 | 0.74 | LRRK2 (0.43) | PDE2APDE10AGRM5HRH3LRRK2 | |
| SCHEMBL13993826 | 0.74 | LRRK2 (0.43) | PDE2APDE10AGRM5HRH3LRRK2 | |
| SCHEMBL7760091 | 0.74 | LRRK2 (0.43) | PDE2APDE10AGRM5HRH3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |