Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 8/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 10/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835268 | 1.00 | ERBB2 (0.49) | ERBB2EPHA2EPHB4FLT1KDR | |
| SCHEMBL17179572 | 1.00 | ERBB2 (0.49) | ERBB2EPHA2EPHB4FLT1KDR | |
| SCHEMBL22598590 | 0.93 | PIK3CD (0.51) | ERBB2EPHA2EPHB4PIK3CDPIK3CA | |
| SCHEMBL29465805 | 0.93 | PIK3CD (0.51) | ERBB2EPHA2EPHB4PIK3CDPIK3CA | |
| SCHEMBL29834734 | 0.88 | PIK3CD (0.62) | ERBB2EPHA2EPHB4PIK3CDPIK3CA | |
| SCHEMBL29834791 | 0.88 | PIK3CD (0.62) | ERBB2EPHA2EPHB4PIK3CDPIK3CA | |
| SCHEMBL665187 | 0.87 | PIK3CD (0.54) | ERBB2EPHA2EPHB4KDRPIK3CD | |
| SCHEMBL2453138 | 0.87 | PIK3CD (0.54) | ERBB2EPHA2EPHB4KDRPIK3CD | |
| SCHEMBL29465791 | 0.87 | PIK3CD (0.54) | ERBB2EPHA2EPHB4KDRPIK3CD | |
| SCHEMBL29465790 | 0.87 | PIK3CD (0.54) | ERBB2EPHA2EPHB4KDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106068262-A | Quinazoline derivant and preparation method thereof and in application pharmaceutically | 四川海思科制药有限公司 | 2016-11-02 | — | — | CN | disclosed |