Methacrylic Acid

Methacrylic Acid

SCHEMBL28835386

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=CC(=O)OCCC[SiH2]OCC.CO[SiH](OC)OC

nearest known ligand 0.47

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 1/20 0.40
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 1/20 0.33
HCAR2 Q8TDS4 3/20 0.33
THRB P10828 2/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28056460 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28068606 0.92 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28257369 0.91 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
Propene SCHEMBL27630347 0.90 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
Alcohol SCHEMBL28248696 0.90 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28112884 0.89 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28113291 0.89 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
Isopropyl Alcohol SCHEMBL28341427 0.88 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28254775 0.86 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27999143 0.86 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106205774-A A kind of electrocondution slurry and transparent conducting coating 哈尔滨工业大学深圳研究生院 2016-12-07 CN claimed