SCHEMBL28835596

SCHEMBL28835596

CCc1[nH]nc(C(=O)Nc2ccc(C3=CCCNC3)cc2)c1C

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.56
SLC6A3 Q01959 1/20 0.56
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HCAR2 Q8TDS4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30324568 0.73 TAAR1 (0.58) TAAR1SLC6A3NPC1RAB9A
Hydrochloric Acid SCHEMBL30324517 0.72 TAAR1 (0.57) TAAR1SLC6A3NPC1RAB9A
SCHEMBL28835666 0.72 TAAR1 (0.54) TAAR1SLC6A3NPC1RAB9AHCAR2
Ralmitaront SCHEMBL19356836 0.71 TAAR1 (1.00) TAAR1SLC6A3
Ralmitaront SCHEMBL29042164 0.71 TAAR1 (0.98) TAAR1SLC6A3
SCHEMBL28835677 0.69 TAAR1 (0.49) TAAR1SLC6A3NPC1RAB9AHCAR2
SCHEMBL28835634 0.69 TAAR1 (0.52) TAAR1SLC6A3NPC1RAB9AHCAR2
Ralmitaront SCHEMBL29042182 0.69 TAAR1 (0.94) TAAR1SLC6A3
Ralmitaront SCHEMBL30042576 0.69 TAAR1 (0.93) TAAR1SLC6A3
SCHEMBL28835645 0.67 TAAR1 (0.49) TAAR1SLC6A3NPC1RAB9AHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874143-A Regulator containing pyrazole derivatives, preparation method and application thereof 上海翰森生物医药科技有限公司 2022-08-09 CN disclosed