Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26910743 | 0.86 | KDM4C (0.46) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL26910771 | 0.81 | KDM4C (0.41) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL11203508 | 0.81 | HCAR2 (0.66) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL17224976 | 0.80 | HCAR2 (0.70) | HCAR2 | |
| Hydrochloric Acid SCHEMBL3094434 | 0.79 | HCAR2 (0.64) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL23305772 | 0.77 | KDM4C (0.50) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL29749406 | 0.77 | KDM4C (0.65) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL14857837 | 0.77 | KDM4C (0.50) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL4714263 | 0.75 | KDM4C (0.49) | HCAR2KDM4CKDM4ESTAT3HIF1A | |
| SCHEMBL19634905 | 0.73 | KDM4E (0.47) | HCAR2KDM4EALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |