Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881120 | 0.87 | MCHR1 (0.59) | MCHR1KCNH2HRH3MAPK14 | |
| SCHEMBL2881864 | 0.85 | MCHR1 (0.64) | MCHR1KCNH2HRH3MAOAMAOB | |
| SCHEMBL2876768 | 0.84 | MCHR1 (0.70) | MCHR1KCNH2HRH3 | |
| SCHEMBL5036980 | 0.84 | MCHR1 (0.63) | MCHR1KCNH2HRH3MAOAMAOB | |
| SCHEMBL2876573 | 0.82 | MCHR1 (0.70) | MCHR1KCNH2 | |
| SCHEMBL2879976 | 0.80 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL2881736 | 0.80 | MCHR1 (0.67) | MCHR1KCNH2HRH3 | |
| SCHEMBL2876464 | 0.80 | MCHR1 (0.64) | MCHR1KCNH2HRH3 | |
| SCHEMBL2879957 | 0.80 | MCHR1 (0.74) | MCHR1KCNH2 | |
| SCHEMBL2881635 | 0.80 | MCHR1 (0.67) | MCHR1KCNH2HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | MCHR1 4/4885KCNH2 2487/4885HRH3 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.