Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881510 | 0.84 | SCN8A (0.43) | L3MBTL1SCN8ASCN10AKDM4EGAA | |
| SCHEMBL27261099 | 0.83 | KDM4E (0.44) | CYP2D6L3MBTL1ABL1KDM4EGAA | |
| SCHEMBL3061823 | 0.79 | GAA (0.50) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM4E | |
| SCHEMBL2882225 | 0.78 | KMT2A (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6L3MBTL1 | |
| SCHEMBL2883959 | 0.77 | KDM4E (0.45) | SLC6A4L3MBTL1KDM4EGAAKMT2A | |
| SCHEMBL12952672 | 0.70 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3L3MBTL1GAA | |
| SCHEMBL15504912 | 0.70 | ABL1 (0.62) | SCN8ASCN10AABL1NPC1SERPINE1 | |
| SCHEMBL28780452 | 0.70 | EPHX2 (0.50) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM4E | |
| SCHEMBL12391777 | 0.69 | CYP2D6 (0.46) | CYP2D6SCN8ASCN10AABL1NPC1 | |
| SCHEMBL5547961 | 0.69 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | SLC6A2 2155/4885SLC6A4 1848/4885SLC6A3 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.