Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.54 |
| ▸ | AXL | P30530 | 2/20 | 0.54 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29817501 | 0.78 | PRKCI (0.59) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL1135006 | 0.78 | PRKCI (0.59) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL18855410 | 0.74 | PRKCI (0.58) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL1356886 | 0.73 | PRKCI (0.67) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL2706554 | 0.72 | ERN1 (0.42) | — | |
| SCHEMBL1749025 | 0.70 | PRKCI (0.62) | PRKCIAXLTTBK1TTBK2JAK2 | |
| SCHEMBL1468832 | 0.70 | PRKCI (0.62) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL2974630 | 0.70 | PRKCI (0.62) | PRKCIAXLTTBK1TTBK2JAK2 | |
| SCHEMBL12561934 | 0.70 | PRKCI (1.00) | PRKCIAXLTTBK1TTBK2JAK1 | |
| SCHEMBL1564932 | 0.70 | PRKCI (0.62) | PRKCIAXLTTBK1TTBK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518096-B | Janus kinase JAK family inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2022-02-11 | — | — | CN | disclosed |