Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883250 | 0.91 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2885589 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1357080 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21385223 | 0.82 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL8020999 | 0.81 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL798095 | 0.81 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2884050 | 0.79 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2880741 | 0.79 | TSHR (0.53) | TSHRHPGDALDH1A1THRBPRKCA | |
| SCHEMBL2883942 | 0.77 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL15458137 | 0.77 | TSHR (0.35) | TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759451-B2 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20070298247-A1 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |