SCHEMBL28837259

SCHEMBL28837259

Oc1ccc(C(CCc2ccccc2O)CCc2ccccc2O)c(O)c1

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYR P14679 4/20 0.47
TAAR1 Q96RJ0 1/20 0.43
KEAP1 Q14145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225915 0.88 TYR (0.61) TYR
SCHEMBL29684410 0.85 TYR (0.50) TYRTAAR1
SCHEMBL2964319 0.85 TYR (0.50) TYRTAAR1
SCHEMBL13206584 0.85 TYR (0.50) TYRTAAR1
SCHEMBL13206585 0.85 TYR (0.50) TYRTAAR1
SCHEMBL13683360 0.80 TYR (0.56) TYR
SCHEMBL24201406 0.76 TYR (0.78) TYRTAAR1
SCHEMBL13683359 0.74 TYR (0.46) TYR
SCHEMBL31545895 0.73 TYR (0.46) TYR
SCHEMBL13976392 0.72 TAAR1 (0.58) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892388-B Synthesis method and application of 3-(2,4-dihydroxy-phenyl)-1,5-bis-(2-hydroxy-phenyl)-pentane-1,5-dione 江南大学 2017-01-25 CN disclosed