Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL2397102 | 0.97 | TSHR (0.78) | TSHRMEN1KMT2ATHRBHTT | |
| Alcohol SCHEMBL2354753 | 0.92 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Octane SCHEMBL8570538 | 0.91 | TSHR (0.70) | TSHRMEN1KMT2ATHRBHTT | |
| Ethylene Glycol SCHEMBL3929160 | 0.91 | TSHR (0.79) | TSHRMEN1KMT2ATHRBHTT | |
| Ethylene Glycol SCHEMBL4669270 | 0.91 | TSHR (0.79) | TSHRMEN1KMT2ATHRBHTT | |
| Ethylene Glycol SCHEMBL28104553 | 0.91 | TSHR (0.79) | TSHRMEN1KMT2ATHRBHTT | |
| Methyl Alcohol SCHEMBL8574712 | 0.90 | TSHR (0.68) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL30673 | 0.90 | TSHR (0.67) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL27130 | 0.90 | TSHR (0.67) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL1133315 | 0.90 | TSHR (0.67) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103597547-B | Containing wax thixotrope can the thick film paste compositions of high aspect ratio silk screen printing | 太阳化学公司 | 2016-12-21 | — | — | CN | disclosed |