Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31659096 | 1.00 | TSHR (0.52) | TSHREP300MEN1CYP3A4KMT2A | |
| SCHEMBL31659092 | 1.00 | TSHR (0.52) | TSHREP300MEN1CYP3A4KMT2A | |
| SCHEMBL11421077 | 1.00 | TSHR (0.52) | TSHREP300MEN1CYP3A4KMT2A | |
| SCHEMBL31659037 | 1.00 | TSHR (0.52) | TSHREP300MEN1CYP3A4KMT2A | |
| SCHEMBL7646026 | 0.98 | TSHR (0.48) | TSHREP300MEN1CYP3A4KMT2A | |
| SCHEMBL9642093 | 0.91 | — | — | |
| SCHEMBL7121091 | 0.91 | — | — | |
| SCHEMBL1555104 | 0.80 | — | — | |
| SCHEMBL1555108 | 0.80 | — | — | |
| SCHEMBL30924809 | 0.79 | TSHR (0.50) | TSHREP300MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901669-A | Selective production of vinyl-and ethyl-functionalized chlorosilanes | 美国陶氏有机硅公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114846017-A | Catalyst particles and process for dehydrosilylation of methyl silanes | 美国陶氏有机硅公司 | 2022-08-02 | — | — | CN | disclosed |