Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632612 | 0.83 | CA12 (0.35) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL10288703 | 0.77 | CA1 (0.49) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL5062188 | 0.74 | CA12 (0.50) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL12510050 | 0.74 | CA12 (0.46) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL22456977 | 0.74 | CA12 (0.46) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL16707916 | 0.72 | CA12 (0.45) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL19757247 | 0.72 | CA12 (0.49) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL17693798 | 0.71 | CA12 (0.47) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL17696366 | 0.71 | CA12 (0.44) | CA12CA1CA2CA9F2RL3 | |
| SCHEMBL10460615 | 0.69 | CA12 (0.46) | CA12CA1CA2CA9F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |