SCHEMBL28839192

SCHEMBL28839192

CC(C)(C)OC(=O)NC1CCN(C(CN)c2ccccc2N)C1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4D Q6B0I6 16/20 0.47
CTSK P43235 2/20 0.44
KCNA3 P22001 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
KDM6A O15550 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28839234 0.83 KDM4D (0.50) KDM4DKDM6A
SCHEMBL19627686 0.82 KDM4D (0.51) KDM4DKCNA3
SCHEMBL19627679 0.80 KCNA3 (0.51) KDM4DCTSKKCNA3
SCHEMBL19627682 0.80 KCNA3 (0.51) KDM4DCTSKKCNA3
SCHEMBL3211686 0.76 PIM1 (0.60) CTSKKCNA3HDAC3HDAC1HDAC2
SCHEMBL14206408 0.76 PIM1 (0.60) CTSKKCNA3HDAC3HDAC1HDAC2
SCHEMBL19627621 0.76 KDM4D (0.52) KDM4DCTSKKCNA3
SCHEMBL19627623 0.76 KDM4D (0.52) KDM4DCTSKKCNA3
SCHEMBL3211670 0.76 PIM1 (0.60) CTSKKCNA3HDAC3HDAC1HDAC2
SCHEMBL1271996 0.74 CKS1B (0.55) CTSKKCNA3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115055066-B Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2023-07-07 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN disclosed