Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 1.00 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.70 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839895 | 0.90 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839230 | 0.89 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29871139 | 0.89 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839269 | 0.89 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839342 | 0.86 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839295 | 0.85 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839361 | 0.85 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839290 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28839270 | 0.83 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839297 | 0.83 | NTRK1 (1.00) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073471-B | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115073471-A | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2022-09-20 | — | — | CN | claimed |
| CN-115073471-B | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115073471-A | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |