Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839288 | 0.90 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839228 | 0.90 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839201 | 0.89 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839900 | 0.89 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839270 | 0.89 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28840133 | 0.87 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL29871055 | 0.86 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28840124 | 0.86 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839292 | 0.86 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL28839895 | 0.85 | NTRK1 (1.00) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073471-B | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115073471-A | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2022-09-20 | — | — | CN | claimed |
| CN-115073471-B | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115073471-A | Pyrazolo tetrahydropyrrole derivative, preparation method and application thereof in medicine | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |