Benzofuran

Benzofuran

SCHEMBL28839906

NNC(=O)NN.c1ccc2occc2c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
CTNNB1 P35222 3/20 0.41
WNT3A P56704 3/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
FLT3 P36888 1/20 0.39
MAOA P21397 1/20 0.37
FTO Q9C0B1 1/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CNR1 P21554 1/20 0.37
HTR1B P28222 2/20 0.36
USP2 O75604 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MITF O75030 1/20 0.36
NCOA1 Q15788 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzofuran SCHEMBL3898681 0.84 CTNNB1 (0.45) MAOBCTNNB1WNT3AALDH1A1FLT3
Benzofuran SCHEMBL3892079 0.82 CTNNB1 (0.47) MAOBCTNNB1WNT3AMAPTALDH1A1
Benzofuran SCHEMBL11121861 0.82 CTNNB1 (0.50) MAOBCTNNB1WNT3AFLT3MAOA
Benzofuran SCHEMBL6244470 0.82 CTNNB1 (0.50) MAOBCTNNB1WNT3AFLT3MAOA
Benzofuran SCHEMBL11121745 0.82 CTNNB1 (0.50) MAOBCTNNB1WNT3AFLT3MAOA
Benzofuran SCHEMBL28034570 0.81 CTNNB1 (0.42) MAOBCTNNB1WNT3AMAPTKDM4E
Benzofuran SCHEMBL28138701 0.80 CTNNB1 (0.45) MAOBCTNNB1WNT3AKDM4EALDH1A1
Benzofuran SCHEMBL27939490 0.80 CTNNB1 (0.49) MAOBCTNNB1WNT3AFLT3MAOA
Benzofuran SCHEMBL28870582 0.80 CTNNB1 (0.45) MAOBCTNNB1WNT3AKDM4EALDH1A1
Benzofuran SCHEMBL27939489 0.80 CTNNB1 (0.49) MAOBCTNNB1WNT3AFLT3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106467478-B Vanillin derivative, preparation method and use containing dithioacetals 贵州大学 2018-05-15 CN disclosed
CN-106467478-A Vanillin derivative containing dithioacetalss, Preparation Method And The Use 贵州大学 2017-03-01 CN disclosed