Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461939 | 0.90 | PIK3CD (0.62) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL17458193 | 0.90 | PIK3CD (0.54) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL17458195 | 0.90 | PIK3CD (0.54) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL17458177 | 0.88 | PIK3CD (0.69) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15816133 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15816135 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15815823 | 0.85 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15815824 | 0.85 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15817655 | 0.85 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA | |
| SCHEMBL15817653 | 0.85 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CGPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459008-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-02-22 | — | — | CN | disclosed |