Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840456 | 1.00 | NPC1 (0.37) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840399 | 0.85 | MRGPRX4 (0.34) | HPGDSMN1; SMN2PYGLMAPTLMNA | |
| SCHEMBL28840432 | 0.84 | HPGD (0.50) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840450 | 0.82 | LRRK2 (0.38) | — | |
| SCHEMBL23706707 | 0.82 | NPC1 (0.40) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840413 | 0.82 | NPC1 (0.35) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840441 | 0.80 | — | — | |
| SCHEMBL23706598 | 0.79 | NPC1 (0.38) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840402 | 0.78 | NPC1 (0.37) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28840830 | 0.77 | AAK1 (0.43) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052856-A | 3-alkoxybenzamide derivative and pest control agent | 组合化学工业株式会社 | 2022-09-13 | — | — | CN | disclosed |